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OCR: n to be Isometric quadriceps force has been sho lults when significantly impaired in GH-deficient a compared with carefully matched contr cle groups however, although data from other mu s not have shown a reduction in force, this w acement statistically different. Following GH rep s has so far therapy, none of the double-blind studi nificant been able to demonstrate a statistically s ases in increase in force, despite significant inc ise of a thigh cross-sectional area (probably beca lled "type II' error). Longer-term but uncontr nonstrate follow-up has, however, been able to de rapy has an increase in quadriceps force when th Lor tinued for over twelve mon